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A quest of the most adverse odds...‏



Whether we are alone in the universe 
is one of the oldest questions humans have pondered.
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For most of history, it has belonged squarely 
in the provinces of religion and philosophy. 

In recent decades, however, 
scientists also have been attracted 
to the problem in increasing numbers. 

Fifty-one years ago, 
a young astronomer by the name of Frank Drake 
began sweeping the skies with a radio telescope 
in the hope of stumbling across a message 
from an alien civilisation. 
Thus began SETI 
-- the Search for Extraterrestrial Intelligence -- 
an ambitious enterprise to survey
thousands of sunlike stars 
in our neighbourhood of the Milky Way galaxy 
for any signs of artificial radio traffic.

When SETI began in 1960, 
it was regarded 
as quixotic at best, 
crackpot at worst. 

"A quest of the most adverse odds," 
was the way distinguished biologist 
George Simpson expressed it. 

The prevailing opinion among scientists 
was that life was the result of a chemical fluke 
so improbable it would be unlikely 
to have happened twice in the observable universe. 

"Life seems almost a miracle," wrote Francis Crick, 
the co-discoverer of the structure of DNA. 

It was echoed 
by another Nobel prizewinning biologist, 
Jacques Monod, in a bleak assessment: 
"Man at last knows that he is alone 
in the unfeeling immensity of the universe, 
out of which he emerged only by chance."

In one of the most astonishing shifts of scientific fashion, 
the consensus today is that the universe is teeming with life. 

Christian de Duve, the Belgian-born biologist 
and another Nobel prizewinner, 
has gone so far as to call life a "cosmic imperative", 
believing it is "almost bound to happen" on any Earth-like planet. 

And where there is life, intelligence may eventually follow. 

In the 1990s, US space agency NASA 
created an astrobiology institute 
to co-ordinate the burgeoning program 
of research into the origin, distribution 
and evolution of life in the universe. 

Although wary of directly funding SETI, NASA 
nevertheless enthusiastically embraces it 
under the broader astrobiology umbrella.

Despite this sea change in thinking, 
there is still not a shred of evidence 
for any life beyond Earth, 
intelligent or otherwise. 

Instead of the hoped-for 
clamour of interstellar messages, 
there is only an eerie silence. 

Why, then, the upbeat assessments from so many scientists? 

Part of the reason 
is the spiralling number of planets 
being discovered orbiting other stars. 

Hundreds have been detected 
using modest ground-based telescopes, 
and still more from a customised satellite named Kepler. 

Planets are not imaged directly 
but inferred through the way they blot out light 
as they cross the face of the parent star 
or cause a detectable wobble in the star from the tug of gravity. 

Although Earth-like planets 
are harder to detect and remain elusive, 
estimates suggest that our galaxy alone 
may contain more than one billion. 

So there is plenty of real estate for life.

It is a fallacy, however, 
that habitable is the same as inhabited. 

To be sure, a planet should be 
reasonably like Earth to support life, 
at least life as we know it. 

But that is far from sufficient. 

The problem 
concerns the origin of life 
and the actual probability 
that it will emerge 
on a typical Earth-like planet. 

A century and a half ago, 
Charles Darwin explained 
how life has evolved 
across billions of years 
from simple microbes 
to the richness and complexity 
of the biosphere we see today. 

But he pointedly left out of his account 
how life got going in the first place. 

"One might as well speculate 
about the origin of matter," he quipped.

Unfortunately, 
the science of biogenesis 
has progressed very little since. 

We still have no idea 
of the pathway that led 
from non-living chemicals 
to the first living cell. 

In fact, we may never have 
a blow-by-blow account of life's origin; 
it happened so long ago 
that all traces must have been obliterated. 

But to answer the question 
about the prevalence of extraterrestrial life 
we merely need to know whether the transition 
from non-life to life is probable or improbable.

Carl Sagan, the charismatic American astronomer 
and ever the optimist, believed that life must arise easily 
because it started on Earth rather quickly. 

Our planet was born 4.5 billion years ago 
amid a disc of gas and dust swirling around the proto-sun. 

But for hundreds of millions of years 
it was pounded by giant asteroids, 
some big enough to boil the oceans 
in the aftermath of their impacts. 

Yet there is good evidence from Western Australia 
that by 3.5 billion years ago life was already well established.

Sadly, Sagan's argument is flawed. 

Our planet will become uninhabitable 
in less than a billion years when the sun 
swells up as it starts to run out of fuel. 

Unless life had started quickly, 
intelligent beings like us 
may never have had time 
to evolve to ask questions 
like "Are we alone?" 
before biology got snuffed out. 

It is therefore impossible to argue, 
from a sample of one selected 
by our very existence, 
that life will always pop up 
readily on earthlike planets.

Some people pin their hopes 
for settling the matter 
on scientists making life in the lab. 

In 1952 the University of Chicago chemist 
Harold Urey persuaded a student, Stanley Miller, 
to try to recreate the conditions 
of the early Earth inside a flask. 

Miller sparked electricity 
through a mix of common gases and water, 
and found that his "primordial soup" 
could make the building blocks of proteins 
within a few days. 

For a while, Miller's experiment 
looked like the first step on the road to life. 

Unfortunately subsequent steps 
have proved a lot harder, 
and most experiments 
in pre-biotic chemistry 
seem to lead to blind alleys. 

The fundamental problem 
is that even the simplest living cell 
is already so fiendishly complex 
it's hard to imagine how it could 
have arisen simply from more 
of the same Miller-Urey processes.

It is worth contrasting Miller's experiment 
with the work of a new breed of "synthetic biologists" 
such as Craig Venter, who helped sequence the human genome. 

Venter and his colleagues have succeeded 
in making novel microbes by inserting 
customised DNA into existing living cells. 

This work is often misrepresented 
as life created in the proverbial test tube, 
but it is very far from that. 

Rather, synthetic biology 
seeks merely to redesign existing life 
by modifying its genetic instructions, 
not to make life from scratch out of basic chemicals.

The latter prospect is a very long way off, 
and even were it to succeed, it would still 
fall short of proving that life arises readily.

It is one thing to make life in a laboratory 
with all sorts of fancy equipment 
operated by an intelligent designer, 
quite another for it to emerge spontaneously 
from a grubby sludge on the sea bed 
-- or wherever it first began.

The popular belief that life starts easily 
in earthlike conditions would immediately 
be verified if we were to find a second sample of it. 

Many astrobiologists think Mars offers a possibility. 

The red planet has been a favourite abode for life 
since the astronomer Percival Lowell thought 
he had glimpsed canals on its surface 
and H.G. Wells wrote War of the Worlds in 1898. 

In the 1970s NASA 
decided to put the matter to the test 
by sending two spacecraft called Viking 
to land on the Martian surface, 
each equipped with experiments 
to sniff out microbes in the soil. 

The landers found a freeze-dried desert 
of highly oxidising dirt bathed 
in deadly ultra-violet radiation 
and protected by a very thin atmosphere.

In spite of the hostile conditions, 
one of the experiments 
gave a strikingly positive result. 

Designed by the organic chemist Gil Levin, 
it used an ingenious technique 
to detect if any bugs in the dirt 
were eating a nutrient broth, 
by looking for radioactively tagged 
carbon dioxide being given off as waste.

The experiment worked repeatedly 
at both landing sites, 
but returned null results 
when the dirt was strongly heated, 
as might be expected if Martian microbes 
were killed by the elevated temperature. 

To this day, Levin maintains 
that he found life on Mars, 
but most astrobiologists are sceptical, 
partly because the other Viking experiments 
were negative or ambiguous, 
and partly because one cannot rule out 
reactive soil chemistry mimicking the results.

Even if Mars is a dead planet today, 
it may not always have been so. 

Survey photographs 
from a series of high resolution orbiters 
show a dramatic landscape sculpted by liquid water. 

Rivers, flood plains, 
gullies, lakes and shorelines 
are conspicuous in the topography. 

On-the-ground analysis 
reveals water ice in the polar caps, 
and fluvial features in the rocks.

Clearly, in the far past 
Mars was warmer 
and wetter than today, 
probably the result 
of massive greenhouse warming 
from an early thick atmosphere 
of carbon dioxide, now 
mostly leaked away into space. 

Hopes remain high that Mars once hosted life, 
though probably no more complex than bacteria.

In 1996 US president Bill Clinton 
electrified the world's press 
when he stood on the White House lawn 
and announced that NASA had evidence of life on Mars 
in the form of a meteorite found in Antarctica, 
containing blobs that resemble tiny bacteria. 

From time to time, 
Mars takes a hit by an asteroid or comet 
with enough force to propel rocks into space. 

A fraction of this ejected debris 
eventually lands on Earth; 
Clinton's meteorite was one of these rocks, 
purportedly containing fossilised microbes. 

However, after years of follow-up studies, 
the evidence for ancient life 
inside the meteorite is very tenuous.

Unless we get lucky and find 
clearer evidence in another meteorite, 
the best hope for detecting traces of life on Mars 
rests with a sample return mission. 

The plan is to send a spacecraft 
that will garner a rag-bag of rocks 
and convey them back to Earth for detailed analysis. 

Unfortunately this ambitious scheme 
has stalled for lack of funding 
and exaggerated concerns 
that the harvested rocks 
might harbour living microbes 
that could trigger a killer plague 
or some other calamity 
if exposed to Earth conditions.

Although the prospects 
for extant life on the Martian surface, 
if not quite zero, are nevertheless slim, 
it remains possible that deep underground 
pockets of microbes may still eke out a living 
in briny aquifers warmed by the planet's internal heat. 

Sketchy evidence for seasonally varying gases 
exuding from the permafrost could point 
to methane-producing subsurface organisms 
like those in similar locations on Earth. 

In the longer term,
a future manned expedition to Mars 
may offer the best hope for settling the issue.

Even if we did obtain 
irrefutable evidence for microbes on Mars, 
it would not of itself prove that life 
is a cosmic imperative, enjoying multiple origins. 

The problem concerns 
the traffic of Martian rocks to Earth, 
which has been going on 
throughout the history of the solar system. 

Cocooned inside a rock, 
protected from the harsh conditions of space 
and shielded from deadly radiation, 
a microbe could probably survive 
the journey between the two planets, 
even if it took millions of years. 

It is very likely that if life did get going on Mars 
billions of years ago when conditions were still favourable, 
then it will have spread to Earth in this manner. 

Indeed, it is possible 
that life on Earth started on Mars
and came here inside Martian meteorites. 

And just as Mars 
may have seeded Earth with life, 
so Earth may have seeded Mars with life, 
because our planet too suffers 
impacts that fling rocks into space. 

The natural cross-contamination of Earth and Mars 
via traded rocks complicates the story of life's origin. 

If we do find evidence for life on Mars, 
it may be the same as earth life 
and point to a single common origin.

The search for a second genesis of life 
may not require anything as expensive 
and challenging as a Mars expedition, however. 

No planet is more earthlike than Earth itself, 
so if life does start up readily in earthlike conditions, 
wouldn't it have begun many times on Earth? 

Could there be traces of a second sample of life right here?

Biology textbooks claim that all life on Earth 
is descended from a common ancestral form.

Evidence cited includes 
many identical features in life's basic machinery, 
such as the universal genetic code 
that implements the instructions 
contained in the four-letter alphabet of DNA. 

But while it is true that all life so far studied 
seems to be related, we cannot be sure 
that fundamentally different forms of life 
may yet be discovered.

The vast majority of terrestrial organisms are microbes, 
and we have only just scratched the surface of the microbial realm. 

You can't tell by looking what makes a microbe tick 
-- you have to study its biochemical innards. 

It is entirely possible that, 
intermingled with bacteria 
and other microbes that lie 
on the same tree of life as you and me, 
are some microbial life forms 
that are radically different 
-- so different that they belong 
not just to another branch 
on the known tree of life, 
but to a separate tree altogether, 
with an independent origin. 

In other words, 
it would be life, 
but not as we know it.

The idea that Earth hosts 
more than one form of life, 
while highly speculative, 
has nevertheless gained 
some traction in recent years, 
and is often dubbed 
the "shadow biosphere", 
or Life 2.0. 

Easiest to spot would be 
if Life 2.0 occupied 
a habitat beyond the reach 
of the hardiest organisms of known life. 

And known life boasts 
some pretty bizarre representatives. 

Microbes have been found 
living near deep ocean volcanic vents 
that thrive in temperatures above 120C. 

Others tolerate extremes 
of salt, acidity, alkalinity or radiation. 

Nevertheless, all these "extremophiles" 
are adaptations of known life. 

If microbes were found living at, say, 180C, 
these would stand out as candidates for Life 2.0.

Much harder would be if the shadow biosphere 
interpenetrated the familiar biosphere. 

In that case Life 2.0 microbes 
might be all around us, 
unidentified for what they are, 
and unresponsive 
to standard biochemical analysis. 

If we did find Life 2.0 here on Earth, 
it would greatly boost 
the search for life in the universe, 
because it would be unlikely 
that life would have started twice 
on one earthlike planet 
and not at all on all the others.

Meanwhile, we should expand our search for ET 
beyond looking for customised radio messages beamed at Earth. 

Any signature of alien technology 
would serve to answer the question 
of whether we are alone in the universe. 

One possibility is to look for radio or optical beacons. 

An advanced civilisation might build a beacon 
to sweep the Milky Way every few months or years, 
perhaps as a monument to its greatness, 
a means of attracting attention, or even as a warning.

A radio beacon would show up as a transient pulse, 
or series of pulses, repeated periodically. 

Bursts of radio waves from deep space have been detected, 
but without follow-up to see whether they are repeated, 
their origin remains unknown. 

We could also look for signs 
of large-scale astro-engineering. 

All technology has an impact 
on its environment; for example, 
global warming from human industry 
could be detected from light years away.

A very advanced alien community 
might have left an imprint, 
not just on its planetary environment, 
but on its astronomical neighbourhood too. 

Telltale signs 
could be artificial structures, 
the depletion of resources 
or the accumulation of waste, 
all of which might be detectable 
through changes in the light from the parent star.

An even more exciting, 
but yet more speculative possibility, 
is that one or more alien civilisations 
has spread beyond its home planet out into the galaxy, 
most likely through robotic probes or self-reproducing machines. 

It is conceivable our own corner or the galaxy 
has been visited, an idea popular 
among UFO enthusiasts and science fiction writers. 

When might this have happened?

At 4.6 billion years, our solar system 
is about a third of the age of the galaxy; 
stars and planets existed long before Earth formed. 

If intelligent life is indeed common, 
then there may be planets 
that hosted advanced civilisations billions of years ago. 

If one of these civilisations sent spacecraft to the solar system, 
there is no reason it would have been in the recent past. 

Most likely it was a very long time ago -- say, 100 million years. 

That raises the fascinating question of what physical traces, 
if any, would survive for 100 million years, even if they were right here on Earth.

Three possibilities come to mind. 

Nuclear waste, perhaps from a nuclear-powered craft, 
if dumped on Earth or the moon would still be detectable 
100 million years later in form of decay products. 

Large-scale mines or quarries, 
though buried beneath overlying rock strata, 
would show up in geological surveys. 

On the moon they might be visible 
from simple photographic surveys 
of the sort now being carried out 
by NASA's Lunar Reconnaissance Orbiter. 

Most tantalising of all, 
products of alien biotechnology, 
such as tinkering with the genomes 
of terrestrial organisms or even 
the creation of a non-competing 
shadow biosphere of Life 2.0 organisms, 
could be found by microbiologists today. 

My favourite is the message in a bottle, 
created in the form of an engineered series of letters 
etched into microbial genomes, which might show up 
during routine gene sequencing research.

Although all these extreme ideas, 
entertaining though they may be, 
almost certainly represent a wild goose chase, 
they may nevertheless be pursued for very little money. 

For example, genomes are being sequenced anyway 
and it costs nothing to do a computer search for anything fishy. 

And cost is the dominating factor 
when doing highly speculative science. 

The jewel in the crown of mainstream SETI 
is a dedicated bank of smallish radio telescopes 
part-paid for by Paul Allen, the co-founder of Microsoft. 

Sadly, in spite of his $US31 million investment, 
the project lacks a partner to fund the $US2m ($1.86m) 
a year running costs, so the Allen Telescope Array 
has been hibernated to await better financial times.

SETI is undeniably a long-shot, but it is one worth undertaking. 

Looking for alien civilisations is really, 
in the words of its founder Frank Drake, 
a search for ourselves, who we are 
and how we fit into the great cosmic scheme of things. 

It is a subject that compels us to address 
the great questions of existence What is life? 
What is intelligence? Is the universe bio-friendly? 
What is the destiny of mankind? 

A society that is too mean-spirited 
to spare a minuscule fraction of its resources 
to reflect on its place in the cosmos 
is a society with an unpromising future.

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